![]() This is why your doctor may have you take a single tablet of hydrocodone every four to six hours while you’re in pain.Įxtended-release formulations last a bit longer, so they are usually taken every 12 hours in order to control pain.įactors that influence how long the effects of hydrocodone lastĪ number of factors can influence the time it takes for hydrocodone to clear the body. You will likely stop “feeling” the pain relief of hydrocodone long before it fully clears your body.
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